The New York Mets (39-34) and Chicago Cubs (24-48) will open up a three-game National League series on Monday night at Wrigley Field, with the first pitch scheduled for 8:05 ET

New York Mets at Chicago Cubs

New York Mets SP Johan Santana has never lost to the Chicago Cubs

New York has played 22 consecutive games against opponents with a .500 or better record, but that streak will end tonight in the Windy City.  The Mets are coming off a disappointing 6-5 home loss to the New York Yankees on ESPN’s Sunday Night Baseball, dropping five of six games in the 2012 Subway Series overall.  Third baseman David Wright is the leading hitter in the majors with a .360 average, but is hitting just .240 in his last seven games at this ball park.  New York is 5-4 as a road favorite of -125 to -150 the last two-plus seasons.

Mets starting pitcher Johan Santana (5-3, 3.00 ERA) has won four of his last five starts, including a 5-0 home win over the Baltimore Orioles, tossing six shutout innings and surrendering four hits.  The left-hander is 1-2 with a 6.37 ERA in six road outings, allowing opponents to hit .280 against him.  In six career games (three starts), Santana has tallied a perfect 3-0 records and 1.65 ERA, serving up just a single home run in 27.1 combined frames.

Chicago has fallen on hard times, losing its last four games of a six-game road trip, including a 5-1 setback to the Arizona Diamondbacks on Sunday afternoon.  “Losing like we’re losing now is tough,” stated Cubs outfielder Alfonso Soriano.  The Cubs have garnered a 14-19 record at home, which is much better than their 10-29 mark on the road.  Offensively, the team ranks 27th in the majors in scoring 264 runs, which signals that it might be time to call up first baseman Anthony Rizzo.  Chicago is 3-16 versus left-handed starters.

Cubs starting pitcher Travis Wood (1-3, 4.14 ERA) earned his first victory of the 2012 MLB campaign last time out, allowing one run and four hits over six frames in a 2-1 road win over the Chicago White Sox.  The left-hander is 0-1 with a 6.11 ERA in three home starts, serving up five home runs in 17.2 combined innings.  Wood surrendered five runs (three earned) on six hits in 4.2 innings of work in his only career start against the Mets on July 5, 2011.

Bettors will likely back the Mets due to their 8-2 record as a favorite, while the Cubs are 2-5 as a home underdog.

Pick:  New York Mets -135

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